BRAIN IMAGING IN NEONATAL HYPOGLYCEMIA

Magnetic resonance imaging studies in two cases of neonatal hypoglycae mia showed cortical and white matter cerebral damage that was most obv ious in the occipital lobes. Both cases showed oedema in the parieto-o ccipital cortex and underlying white matter in the acute phase, with p rofound atrophy of these regions in the chronic phase. These findings support those of pathological studies which suggest that hypoglycaemia induces cerebral damage by a mechanism separate from the effects of c erebral hypoxia-ischaemia caused by secondary seizures.