LEYDIG-CELL THE OVARIAN STROMA

We report the case of a 63-year-old, menopausal patient, yielding hirs utism an associated with clinical virilization. Biological data eviden ced an increased androgen production (plasma testosterone at 1.8 and 2 .1 ng/ml). Radiological exams (ultrasonography, CT Scan and MRI Scan) failed to find any ovarian tumor, which led to perform an ovarian sele ctive venous percutaneous catheterization. A stromal Leydig cell tumor , associated with a hilar leydigian hyperplasia, was evidenced in path ology. Clinical, biological, radiological and pathological data are su ccessively discussed. Pathophysiology of Leydig cell tumor, particular ly when located in the ovarian stroma, is also reviewed.