REGIONAL CEREBRAL BLOOD-FLOW IN PEDIATRIC MOYAMOYA-DISEASE - AGE-DEPENDENT DECLINE IN SPECIFIC REGIONS

Thirteen pediatric patients (ages 4-13 years) who underwent surgical t reatment were examined regarding their rCBF in the preoperative period s. The postoperative rCBF was measured 39 times in these 13 patients. Thirteen healthy normal subjects (ages from 6 to 21 years) were also e xamined. The rCBF in the operculum and in the frontal, parietal, and o ccipital lobes was measured with Xe-133 inhalation method and single p hoton emission computed tomography. In the parietal and occipital lobe s, the preoperative rCBF had a negative and significant correlation wi th their ages, but not in the operculum or frontal lobe, However, subs equent to the surgical treatment, the I CBF increased significantly in the patients 5 years old or less, and then post-operative rCBF values had significant negative correlations with age in each region.