Objective-To describe function and identify factors that affect outcom
e in dogs undergoing limb salvage surgery for osteosarcoma (OS) of the
proximal humerus. Study Design-A retrospective study of dogs in which
OS of the proximal humerus was treated with limb salvage surgery. Ani
mals-17 client-owned dogs. Methods: Records were analyzed for function
al outcome, recurrence, metastasis, and survival. Results-Outcome was
good to excellent in 12% of dogs. Recurrence, metastasis, and survival
were significantly affected by completeness of surgical margins. Doub
le plating of the distal allograft-host junction significantly reduced
frequency of biomechanical failure. Conclusions-Limb salvage surgery
for OS of the proximal humerus did not result in acceptable function a
nd was fraught with postoperative complications. Outcome was significa
ntly affected by completeness of surgical margins. Clinical Relevance-
Limb salvage surgery for OS of the proximal humerus in dogs cannot be
recommended until improvement in functional outcome and reduction in p
ostoperative complications can be achieved. The dependence of outcome
on completeness of surgical margins supports aggressive en bloc resect
ion and marking and evaluating surgical margins. (C) Copyright 1998 by
The American College of Veterinary Surgeons.