The hepatic CYP1A1 (ethoxyresorufin-O-deethylase (EROD) and protein le
vel) in rainbow trout and eelpout was induced by isosafrole, beta-naph
thoflavone, 3,3',4,4'-tetrachlorobiphenyl and mixtures of two of the c
ompounds. A potentiation effect of the CYP1A1 response was observed wh
en isosafrole was given together with beta-naphthoflavone, but not whe
n isosafrole was given with 3,3',4,4'-tetrachlorobiphenyl. (C) 1998 El
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