NEW METHODS OF RESOLUTION OF RACEMIC DIOLS USING (S)-PROLINE

Authors
PERIASAMY M RAMANATHAN CR PRASAD ASB KANTH JVB
Citation
M. Periasamy et al., NEW METHODS OF RESOLUTION OF RACEMIC DIOLS USING (S)-PROLINE, Enantiomer, 3(1), 1998, pp. 3-7
Citations number
15
Categorie Soggetti
Chemistry,"Chemistry Inorganic & Nuclear",Biology
Journal title
Enantiomer → ACNP
ISSN journal
10242430
Volume
3
Issue
1
Year of publication
1998
Pages
3 - 7
Database
ISI
SICI code
1024-2430(1998)3:1<3:NMOROR>2.0.ZU;2-H
Abstract
Racemic 1,2-diphenyl-1,2-ethanediol is resolved to obtain (S,S)-isomer in 99% ee through complexation with boric acid and (S)-proline. The r acemic 1,1,2-triphenyl-1,2-ethanediol has been resolved to give (S)iso mer in 94% ee using (S)-proline alone by refluxing in benzene.