GLYCOSIDOPYRROLES PART 3 - EFFECT OF THE BENZOCONDENSATION ON ACYCLICDERIVATIVES - 1-(2-HYDROXYETHOXY)METHYLINDOLES AS POTENTIAL ANTIVIRALAGENTS

Authors
ALMERICO AM BARRAJA P DIANA P CIRRINCIONE G MINGOIA F MUSIU C PERRA G PUTZOLU M MARONGIU ME
Citation
Am. Almerico et al., GLYCOSIDOPYRROLES PART 3 - EFFECT OF THE BENZOCONDENSATION ON ACYCLICDERIVATIVES - 1-(2-HYDROXYETHOXY)METHYLINDOLES AS POTENTIAL ANTIVIRALAGENTS, Il Farmaco, 53(6), 1998, pp. 409-414
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
53
Issue
6
Year of publication
1998
Pages
409 - 414
Database
ISI
SICI code
0014-827X(1998)53:6<409:GP3-EO>2.0.ZU;2-U
Abstract
The new of 1-(2-hydroxyethoxy) methylindole derivatives 3a-i were prep ared in good yields. None of them showed any significant anti-HIV acti vity and therefore the benzocondensation between the 2 and 3 positions of the pyrrole ring definitely reduced the weak activity found in the analogues 1a-c. (C) 1998 Elsevier Science S.A. All rights reserved.