Diarrhea is a non-specific symptom which may be associated with Addiso
n's disease and several causes had been demonstrated in the aetiology.
We describe a patient with Addison's disease who was suffering from c
hronic diarrhea for three months. She was diagnosed as having collagen
ous colitis and successfully treated with Sulphasalazine, 2 g/day. Col
lagenous colitis is an uncommon cause of chronic diarrhea and the asso
ciation of collagenous colitis with Addison's disease has not previous
ly been described. We think that collagenous colitis may play a sole i
n the aetiology of diarrhea in patients with Addison's disease and the
refore we suggest a full colonoscopic examination in other patients wi
th Addison's disease and diarrhea to determine the incidence of collag
enous colitis in the aetiology of diarrhea.