THE IN-VITRO MOTILITY RESPONSE TO VARIOUS ANTHELMINTICS OF 3RD-STAGE LARVAE OF OESOPHAGOSTOMUM SPP. FROM PIGS

The in vitro activities of thiabendazole, levamisole, pyrantel, morant el and ivermectin against Oesophagostomum spp., the nodular worm of pi gs, were determined and compared. The study was carried out using isol ates of O. dentatum and O. quadrispinulatum, which had been defined in vivo. Infective larvae were exposed to the anthelmintics for 24 h and then placed in a micromotility meter. All the treatments significantl y reduced the motility of the ensheathed L-3 larvae, but the micromoti lity meter was not able to differentiate between anthelmintic resistan t and anthelmintic susceptible isolates.