A NEW LIGAND ALPHA-AMINO-ACID - )-2-AMINO-3-[1-(1,4,7-TRIAZACYCLONONANE)]PROPANOIC ACID

Authors
ROSSI P FELLUGA F SCRIMIN P
Citation
P. Rossi et al., A NEW LIGAND ALPHA-AMINO-ACID - )-2-AMINO-3-[1-(1,4,7-TRIAZACYCLONONANE)]PROPANOIC ACID, Tetrahedron letters, 39(39), 1998, pp. 7159-7162
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
39
Year of publication
1998
Pages
7159 - 7162
Database
ISI
SICI code
0040-4039(1998)39:39<7159:ANLA-)>2.0.ZU;2-7
Abstract
The title amino acid was obtained by regiospecific ring-opening reacti on of Boc-diprotected 1,4,7-triazacyclononane with (S)-2-beazyloxycarb onylamino-beta-lactone 80% isolated yield) followed by deprotection. I t strongly binds transition metal ions like Zn and Cu-II and can be in corporated in peptide sequences without affecting the metal ion affini ty of the triazamacrocycle. (C) 1998 Elsevier Science Ltd. All rights reserved.