The objective of the present study was the defined preparation and cha
racterization of various oxide layers on titanium, Ti6Al7Nb and Ti6Al4
V. Immobilization techniques for collagen and hydroxyapatite Ca-10(PO4
)(6)(OH)(2), the main components contacting an implant within the huma
n body, were tested. The oxide layers were created by electrochemical
polarization in phosphate buffer solutions. The thickness of the layer
s depended on the formation potential. We found a thickness/potential
relation of approximately 2.2 nm/V. At formation potentials up to 80 V
anatase was the only titanium dioxide modification traceable by Raman
spectroscopy and XRD. The electrochemically assisted deposition of hy
droxyapatite on these surfaces starts with an amorphous product which
can be monitored by SEM, IR and Raman spectroscopy. The immobilization
of collagen followed by anodic electrochemical polarization results e
ither in partial integration of collagen fibrils into the oxide layer
or at least in a strong increase-of the interaction force between TiO2
and the collagen fibrils.