Oestrus was synchronised in 15 nondescript goats with two injections o
f 7.5 mg luprostiol given II days apart. They mere randomised into two
groups; nine (group 1) received 3 mi charcoal-extracted buffalo folli
cular fluid at 12 hour intervals on days 12 to 15 of the cycle and six
(group 2) received an equal volume of normal saline at the same times
. Luteolysis was induced 96 hours after the treatments began by a sing
le injection of 7.5 mg luprostiol. The onset of oestrus mas detected u
sing a vasectomised buck and the ovarian response was determined by vi
sual observation of the ovaries following a midventral laparotomy perf
ormed five or six days after oestrus. In the goats of group 1, oestrus
occurred 99.3 (4.13) hours after the injection of luprostiol, and in
the goats of group 2 after 68.0 (6.7) hours. Group 1 does had signific
antly more ovulations (2.56 [0.29]) and large greater than or equal to
5 mm diameter) unovulated follicles (2.77 [0.40]) than the does of gr
oup 2 which had 1.83 (0.16) ovulations and 0.50 (0.34) large unovulate
d follicles.