L. Mayfield et al., ROOT CONDITIONING USING EDTA GEL AS AN ADJUNCT TO SURGICAL THERAPY FOR THE TREATMENT OF INTRAOSSEOUS PERIODONTAL DEFECTS, Journal of clinical periodontology, 25(9), 1998, pp. 707-714
The aim of this clinical study was to compare the treatment outcome fo
llowing root surface conditioning using an EDTA gel preparation in con
junction with surgical therapy with that following conventional flap s
urgery in periodontal intraosseous defects. 36 patients, each of them
contributing one intraosseous defect greater than or equal to 4 mm in
depth participated. Defect sites had a probing pocket depth greater th
an or equal to 5 mm and bled on probing following hygienic treatment p
hase. No furcation involvement or endodontic complications were presen
t. In the EDTA group, 18 consecutive patients, defects were treated by
root conditioning with EDTA gel for 3 minutes in combination with sur
gical therapy. In the control group, 18 patients, conventional flap su
rgery was performed without root conditioning. Chlorhexidine rinsings
0.2% were prescribed following surgery for 2-3 weeks with modified ora
l hygiene instruction. A strict recall program was implemented includi
ng professional prophylaxis and oral hygiene reinforcement every 4-6 w
eeks until 6-month re-evaluation. Baseline probing pocket depths and d
efect depths of 7.1+/-1.3 mm and 6.9+/-1.6 mm in the EDTA group and 7.
6+/-1.9 mm and 6.6+/-1.7 mm, respectively, in the control group were m
easured. 6-month clinical results showed a significant probing attachm
ent level gain of 1.8+/-1.5 mm and 1.0+/-1.7 mm in the EDTA and contro
l groups respectively. A probing bone gain of 1.0+/-1.3 mm in the EDTA
group was measured with a non-significant gain of 0.4+/-1.2 mm in the
control group. Radiographic analysis confirmed these results. There w
ere no statistically significant differences in treatment outcome betw
een the group treated by root conditioning in combination with flap su
rgery and conventional flap surgery alone.