The purpose of this study was to evaluate the results of myopic photor
efractive keratectomy (PRK) with or without astigmatic keratotomy (AK)
for different levels of intended correction by using the SVS Apex las
er, Methods, This is a retrospective cohort study of 226 eyes that had
PRK for myopia ranging from -1.0 to -7.6 diopters and 6 months of fol
low-up. In addition, 64 of these eyes had AK for naturally occurring o
r laser-induced astigmatism. Uncorrected visual acuity, spectacle-corr
ected visual acuity, and corneal topography with quantitative descript
ors of surface regularity (SRI) and surface asymmetry (SAI) were used
to monitor the results of PRK with or without AK. Results, At 6 months
, 95.6% eyes had an uncorrected visual acuity of 20/40 or better, 90%
eyes were within +/-1.0 diopter of emmetropia, and 3.1% eyes lost two
lines of best-corrected vision. No eyes lost more than two lines of be
st-corrected vision. Mean refractive astigmatism was reduced, but mean
SAI and SRI were increased, 6 months after PRK. Uncorrected vision, b
est-corrected vision, and predictability decreased, whereas SAI and SR
I increased, with increasing attempted correction. Conclusion, PRK, wi
th or without AK, effectively reduced myopia in all eyes by 6 months a
fter surgery. Predictability tended to decrease with increasing attemp
ted correction, even for eyes with relatively low to moderate myopia.
PRK may induce surface asymmetry and irregularity at 6 months, and the
se alterations tend to be greater as the attempted correction increase
s.