Five patients with adverse reactions to peak flow monitoring are prese
nted: 2 patients had herniation of abdominal content, while the others
presented with vasovagal syncope, minor depression and neurotic preoc
cupation with peak flow values, respectively. As a result, 3 of the 5
patients became noncompliant. For nonpsychological somatic adverse rea
ctions, we calculated an incidence of 1.1 cases/1,000 patients started
on peak flow monitoring, Adverse reactions with a psychological backg
round may be more frequent. Clinicians should bear in mind that patien
ts noncompliant with peak flow monitoring may have discontinued becaus
e of adverse reactions.