VACCINATION OF RABBITS AGAINST TRICHOPHYTOSIS - AN EXPERIMENTAL-STUDY

Protective efficacy of TRICHOPELEN, a vaccine containing a living Tric hophyton mentagrophytes strain, against experimental infection with T. mentagrophytes strain proved good. The vaccine showed a satisfactory effect after i.m. administration to I-month old rabbits and after s.c. administration to 11- to 14-day old rabbits. The efficacy of TRICHOBE N AV, a vaccine containing a living T. verrucosum strain, against the heterologous species T. mentagrophytes was unsatisfactory. The Vaccina tion T. mentagrophytes strain survived in the inoculated muscle of exp erimental rabbits for 9 to 10 days. Examination of the lungs, liver, k idney, spleen, lymph node and blood samples for the presence of the Va ccination strain yielded negative results.