The feline blood-group system embraces three blood types: TYPe A which
occurs most frequently, Type B which frequency largely varies it depe
nds from the race, and the extremely seldom Type AB. The allele A is d
ominantly transmitted by the allele B, and the blood type AB is transm
itted separately. Cats have naturally occuring isoantibodies, especial
ly Type B cats have very strong anti A antibodies which are clinically
responsible for two incompatibility reactions. Feline neonatal isoery
throlysis occurs in type A puppies of cats with blood type B. A-B inco
mpatible transfusions are not efficient and lead above all to severe a
cute haemolytic reactions. These incompatibility reactions can be prev
ented by a preceding blood-typing or blood-cross-test. Only A-B compat
ible blood may be transfused and cats with blood type B should only be
mated with type B tomcats.