Imaging plays an important role in evaluating fortuitously discovered
adrenal masses. These unanticipated masses (incidentalomas) are usuall
y discovered at CT examinations. Although most incidentally discovered
adrenal tumors are nonhyperfunctioning adenomas, they must be disting
uished from primary or secondary malignant lesions. Recent studies hav
e established that both unenhanced CT scans and chemical shift MR imag
ing can accurately differentiate benign adenomas from nonadenomatous m
asses by features that reflect the large amount of lipid found in most
adenomas and absent in most nonadenomas. We review here the current i
maging issues concerning adrenal incidentalomas including diagnostic a
pproaches and management.