MALIGNANT-LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID-TISSUE IN THE LARYNX

A 36-year-old woman was referred to the department of Otolarvngology/H ead and Neck Surgery, University Hospital Vrije Universiteit, because of complaints of hoarseness. A submucosal swelling of the right ventri cular fold was found that was subsequently biopsied. Histopathological examination showed a low-grade B-cell non-Hodgkin's lymphoma of mucos a-associated lymphoid tissue (MALT). Treatment consisted of local radi otherapy (to 2800 cGy). During the 2-year follow-up to date there has been no evidence of recurrent disease. To our knowledge, only four cas es of MALT lymphomas in the larynx have been reported. The clinical be havior of MALT lymphoma is clearly quite distinct and requires proper recognition to prevent inadvertent misdiagnosis or overtreatment.