A NOVEL ROUTE TO THE GEISSOSCHIZINE SKELETON - THE INFLUENCE OF LIGANDS ON THE DIASTEREOSELECTIVITY OF THE HECK CYCLIZATION

Authors
BIRMAN VB RAWAL VH
Citation
Vb. Birman et Vh. Rawal, A NOVEL ROUTE TO THE GEISSOSCHIZINE SKELETON - THE INFLUENCE OF LIGANDS ON THE DIASTEREOSELECTIVITY OF THE HECK CYCLIZATION, Tetrahedron letters, 39(40), 1998, pp. 7219-7222
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
40
Year of publication
1998
Pages
7219 - 7222
Database
ISI
SICI code
0040-4039(1998)39:40<7219:ANRTTG>2.0.ZU;2-B
Abstract
A concise, novel route to the geissoschizine skeleton has been develop ed. The key step involves a Heck cyclization reaction, which was found to lead to opposite diastereomers, (+/-)-8 or (+/-)-9, depending on t he reaction conditions. (C) 1998 Elsevier Science Ltd. All rights rese rved.