Vb. Birman et Vh. Rawal, A NOVEL ROUTE TO THE GEISSOSCHIZINE SKELETON - THE INFLUENCE OF LIGANDS ON THE DIASTEREOSELECTIVITY OF THE HECK CYCLIZATION, Tetrahedron letters, 39(40), 1998, pp. 7219-7222
A concise, novel route to the geissoschizine skeleton has been develop
ed. The key step involves a Heck cyclization reaction, which was found
to lead to opposite diastereomers, (+/-)-8 or (+/-)-9, depending on t
he reaction conditions. (C) 1998 Elsevier Science Ltd. All rights rese
rved.