SYNTHESIS OF 6-AMYLSALICYLIC ACID FROM 3-AMSALDEHYDE - CONVERSION OF PHTHALIDE TO THIOPHTHALIDE BY ALUMINUM HALIDE-BUTANETHIOL

Authors
NISHIKAWA A HASHIMOTO Y SHIRAI R
Citation
A. Nishikawa et al., SYNTHESIS OF 6-AMYLSALICYLIC ACID FROM 3-AMSALDEHYDE - CONVERSION OF PHTHALIDE TO THIOPHTHALIDE BY ALUMINUM HALIDE-BUTANETHIOL, Tetrahedron letters, 39(40), 1998, pp. 7307-7308
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
40
Year of publication
1998
Pages
7307 - 7308
Database
ISI
SICI code
0040-4039(1998)39:40<7307:SO6AF3>2.0.ZU;2-E
Abstract
The Lewis acid-promoted reaction of 3-butyl-7-methoxyphthalide with bu tanethiol gave the thiophthalide, which was converted to 6-amylsalicyl ic acid by alkaline hydrolysis and successive desulfurization by Raney Ni. (C) 1998 Elsevier Science Ltd. All rights reserved.