STEREOCONTROLLED CYCLIZATION OF ENYNOLS AND ALLENYNOLS WITH (ETA(2)-PROPENE)TI(O-I-PR)(2) - IMPORTANT ROLE OF UNPROTECTED HYDROXY GROUP AT A REMOTE POSITION

Authors
URABE H SATO F
Citation
H. Urabe et F. Sato, STEREOCONTROLLED CYCLIZATION OF ENYNOLS AND ALLENYNOLS WITH (ETA(2)-PROPENE)TI(O-I-PR)(2) - IMPORTANT ROLE OF UNPROTECTED HYDROXY GROUP AT A REMOTE POSITION, Tetrahedron letters, 39(40), 1998, pp. 7329-7332
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
40
Year of publication
1998
Pages
7329 - 7332
Database
ISI
SICI code
0040-4039(1998)39:40<7329:SCOEAA>2.0.ZU;2-X
Abstract
Stereochemistry of (eta(2)-propene)Ti(O-i-Pr)(2)-mediated cyclization of enynols and allenynols is efficiently controlled by their remote hy droxy group, showing good diastereaselectivities as high as 82:18-98.5 :1.5, which are uniformly superior to those observed for the correspon ding t-BuMe2Si ethers. (C) 1998 Elsevier Science Ltd. AII rights reser ved.