INFLUENCE OF LIPID-COMPOSITION ON PEDIOCIN PA-1 BINDING TO PHOSPHOLIPID-VESICLES

Authors
CHEN YH LUDESCHER RD MONTVILLE TJ
Citation
Yh. Chen et al., INFLUENCE OF LIPID-COMPOSITION ON PEDIOCIN PA-1 BINDING TO PHOSPHOLIPID-VESICLES, Applied and environmental microbiology, 64(9), 1998, pp. 3530-3532
Citations number
17
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Applied and environmental microbiology → ACNP
ISSN journal
00992240
Volume
64
Issue
9
Year of publication
1998
Pages
3530 - 3532
Database
ISI
SICI code
0099-2240(1998)64:9<3530:IOLOPP>2.0.ZU;2-O
Abstract
Pediocin PA-1 bound to anionic lipid vesicles with saturated or unsatu rated fatty acid chains in a lipid concentration-dependent fashion. Li ttle change in binding parameters was observed for zwitterionic lipid vesicles. Decreasing the anionic lipid content of the vesicles gave a higher relative dissociation constant for the peptide-lipid interactio ns and further supports the electrostatic interaction model of binding .