Ns. Litofsky et al., MERKEL CELL-CARCINOMA OF THE EXTERNAL AUDITORY-CANAL INVADING THE INTRACRANIAL COMPARTMENT, American journal of otolaryngology, 19(5), 1998, pp. 330-334
Purpose: To report an unusual case of an intracranial extension of Mer
kel cell carcinoma originating in the external ear canal and causing n
eurological deficits. Case Report: An 86-year-old woman, with a 16-mon
th history of an external auditory canal mass, presented with hemipare
sis, facial paralysis, and obtundation. Radiographic images showed an
intracranial mass extending into the petrous bone. Method: The patient
had a craniotomy for intracranial tumor resection with concurrent mas
toidectomy for facial nerve decompression and obtundation and hemipare
sis were resolved. Residual tumor was subsequently treated with adjuva
nt radiation therapy, and facial nerve function consequently improved.
Conclusion: Merkel cell tumors rarely invade the intracranial compart
ments. Residual tumor and neurological deficits may respond to adjuvan
t radiation therapy. Copyright (C) 1998 by W.B. Saunders Company.