Citation
E. Jones et M. Goldman, LIPID FORMULATIONS OF AMPHOTERICIN-B, Cleveland Clinic journal of medicine, 65(8), 1998, pp. 423-427
Citations number
6
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
08911150
Volume
65
Issue
8
Year of publication
1998
Pages
423 - 427
Database
ISI
SICI code
0891-1150(1998)65:8<423:LFOA>2.0.ZU;2-7
Abstract
Amphotericin B has long been the mainstay in the treatment of systemic
fungal infections, but its nephrotoxicity limits the dosage that can
be used. New lipid-based forms may allow higher dosing with less nephr
otoxicity. Unfortunately, these new forms are substantially more expen
sive, and data from randomized clinical trials of their relative effic
acy are as yet limited.