MIGRATION OF DI-(2-ETHYLHEXYL) PHTHALATE FROM PVC CHILD ARTICLES INTOSALIVA AND SALIVA SIMULANT

A simple migration test and a more complicated simulation of children' s sticking and biting was used to establish migration of DEHP from PVC child-use articles into saliva and compared to a mimic test. The stat ic migration test of a film containing approximately 30% DEHP with sal iva simulant gave the lowest values of DEHP; simple shaking increased the amounts of DEHP from 25 +/- 8 to 499 +/- 153 mu g/g film. The more complicated arrangements to simulate sticking and biting are not so s uitable for standard applications. When comparing the in vitro migrati on tests with the mimic test the factors were 25 and 29 for the static tests (3 and 6 hours) and 1.4 for the shaking test.