Large abdominal wall defects may require a prosthesis for closure. The
aim of our study was to identify the best material for abdominoplasty
in pediatric patients. One hundred twenty-eight Wistar KY strain male
rats (3 weeks old) were used. All animals underwent celiotomy via a m
idline skin incision. They were divided into seven groups as follows:
the animals in groups 1 through 6 underwent full-thickness abdominal w
all excision 3 cm in diameter. The animals in group 1 underwent primar
y closure. In groups 2 through 6 the defect was closed with prosthetic
material. In Group 7, a sham operation was performed. Daily weights w
ere measured. The animals were killed after 3 and 9 weeks. Adhesion sc
ores were assigned for each group. Vicryl mesh resulted in the fewest
adhesions and had no effect on weight gain in the developing rats.