Ea. Davies et al., RESEARCH NOTE - THE EFFECT OF PH ON THE STABILITY OF NISIN SOLUTION DURING AUTOCLAVING, Letters in applied microbiology, 27(3), 1998, pp. 186-187
Contrary to previous documentation,it has been shown that nisin soluti
on is not stable to autoclaving at pH 2. It is most stable at pH 3 (<
j% activity loss at 115 degrees C 20 min(-1)), while all values below
and above this show a marked decrease in activity, especially those fu
rthest removed from pH 3.