Accurate alignment of knee implants is essential for the success of to
tal knee replacement. Although mechanical alignment guides have been d
esigned to improve alignment accuracy, there are several fundamental l
imitations of this technology that will inhibit additional improvement
s. Various computer assisted techniques have been developed to examine
the potential to install knee implants more accurately and consistent
ly than can be done with mechanical guides. For example, computer inte
grated instrumentation incorporates highly accurate measurement device
s to locate joint centers, track surgical tools, and align prosthetic
components. Image guided knee replacement provides a three-dimensional
preoperative plan that guides the placement of the cutting blocks and
prosthetic components. Robot assisted knee replacement allows one to
machine bones accurately without the use of standard cutting blocks. T
he rationale for the development of computer assisted knee replacement
systems is presented, the operation of several different systems is d
escribed, the advantages and disadvantages of different approaches are
discussed, and areas for future research are suggested.