Stereotypic movement disorders (SMD) such as head-banging, which are c
ommon among children with mental retardation or pervasive developmenta
l disorders, may also occur in intellectually normal adults. We report
a 27-year history of daily head-banging with self-injury in a 49-year
-old man with normal cognition. The patient had no personal or family
history of Tourette's syndrome, tic disorder, obsessive-compulsive dis
order (OCD), or mental retardation. The frequency of his stereotypical
head-banging increased with anxiety, loud noises with startle, and bo
redom. He reported a sense of pleasure from his head-banging, and the
frequency of this behavior decreased when he was treated with the opio
id antagonist naltrexone. Although not diagnostic, the self-stimulator
y or pleasurable component of head-banging, body-rocking, thumb-suckin
g, and other SMD may help distinguish them from ties, Tourette's syndr
ome, OCD, and deliberate self-harming behavior. This report reviews th
e disorders associated with SMD and discusses the potential mechanisms
for these behaviors. The treatment of SMD includes drugs that work th
rough opioid, serotonergic, or dopaminergic systems.