Purpose: Thoracocardiography noninvasively monitors global stroke volu
me by inductive plethysmographic recording of ventricular volume curve
s as previously validated by thermodilution. Our purpose was to invest
igate the potential of thoracocardiography to individually assess stro
ke volume of the left ventricle. We hypothesized that curves predomina
ntly reflecting left ventricular volume could be obtained by recording
waveforms from thoracocardiographic transducers placed at various lev
els around the chest, and by identifying their origin as the left vent
ricle if mean expiratory exceeded mean inspiratory stroke volumes duri
ng spontaneous breathing. Materials and Methods: Stroke volumes obtain
ed by thoracocardiography in normal subjects were compared beat by bea
t with estimates derived from simultaneous measurements of left ventri
cular cavity stroke area by echocardiography with automatic boundary d
etection. Changes in respiratory variations of stroke volumes were ana
lyzed during spontaneous breathing at fixed rate and tidal volume, dur
ing mechanical ventilation, and resistive loaded breathing. Results: I
n 170 comparisons of beat-by-beat stroke volumes, 89% of thoracocardio
graphic fell within +/- 20% of echocardiographic estimates. Changes in
tidal volume, resistive loaded breathing, and mechanical ventilation
induced respiratory variations of thoracocardiographic derived stroke
volumes consistent with the known effect of respiratory changes in int
rapleural pressure on left ventricular stroke volumes. Conclusions: Th
e results suggest that thoracocardiography noninvasively tracks change
s in left ventricular stroke volumes. Their absolute value may also be
monitored if an initial calibration by an independent technique, such
as echocardiography, is performed. Copyright (C) 1998 by W.B. Saunder
s Company.