D. Spiegel et al., COMPARISON OF THE EFFICACY OF ER-YAG LASER SCLEROSTOMY AB EXTERNO VERSUS TRABECULECTOMY IN THE TREATMENT OF PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA, Der Ophthalmologe, 95(8), 1998, pp. 537-541
Purpose: This study was conducted to compare the efficacy of the Er-YA
G laser sclerostomy ab externo versus trabeculectomy in the treatment
of primary open - angle glaucoma. Methods: Twelve patients with POAG u
nderwent ab externo laser sclerostomy using an Er-YAG laser (Sklerosto
m 2.9(R); lambda = 2940 nm, t = 200 mu s, 2 Hz, 400 mu m, 15 mJ). Only
local medication was used, and there were no risk factors for failure
. As a control group 12 patients out of 248 standardized trabeculectom
ies were matched in terms of age, sex, diagnosis and local medications
. No antimetabolites were used in either group. Results: After a follo
w-up of 9 months in the sclerostomy group 53%; (7/12; P = 0.03) showed
a patent fistula in comparison of 100% in the trabeculectomy group. T
here was a significantly lower mean IOP during the first postsurgical
week in the group of sclerostomies (3.6 +/- 1.5 mmHg versus 7.5 +/- 2.
7 mmHg; P = 0.0001) with a higher incidence of choroidal detachments (
9/12 versus 2/12; P = 0.004). The choroidal detachments lasted longer
in the sclerostomy group (3.5 months versus 0.3 months; P = 0.014). Ir
is incarcerations were found only in sclerostomies (7/12; P = 0.05). C
onclusions: Based on these findings, Er-YAG laser sclerostomy prooved
to be less effective than trabeculectomy in the treatment of glaucoma
patients. Er-YAG laser sclerostomies were associated with a higher inc
idence of postsurgical complications such as hypotony, choroidal detac
hments and iris incarcerations. At this point Er-YAG laser sclerostomy
is not superior to conventional trabeculectomy.