PARASITE GLYCOCONJUGATES .1. THE SYNTHESIS OF SOME EARLY AND RELATED INTERMEDIATES IN THE BIOSYNTHETIC-PATHWAY OF GLYCOSYL-PHOSPHATIDYLINOSITOL MEMBRANE ANCHORS

Authors
COTTAZ S BRIMACOMBE JS FERGUSON MAJ
Citation
S. Cottaz et al., PARASITE GLYCOCONJUGATES .1. THE SYNTHESIS OF SOME EARLY AND RELATED INTERMEDIATES IN THE BIOSYNTHETIC-PATHWAY OF GLYCOSYL-PHOSPHATIDYLINOSITOL MEMBRANE ANCHORS, Journal of the Chemical Society. Perkin transactions. I, (23), 1993, pp. 2945-2951
Citations number
44
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
23
Year of publication
1993
Pages
2945 - 2951
Database
ISI
SICI code
0300-922X(1993):23<2945:PG.TSO>2.0.ZU;2-8
Abstract
The enantio-pure 1D- and 1L-MYO-inositol derivatives 3D and 3L have be en used to prepare sodium 1 amino-2-deoxy-alpha-D-glucopyranosyl)-myo- inositol sn-2,3-dipalmitoyloxypropyl phosphate 21 and a related 1,6-di substituted 1 L-MYO-inositol 28, respectively. The hydrogenphosphonate approach was effective in coupling together the phosphonolipid moiety 16 and the protected zido-2-deoxy-alpha-D-glucopyranosyl)-myo-inosito ls 15 and 24, respectively.