INFANTS WITH BIRTH-WEIGHT 1,000-1,499 GRAMS BORN IN 3 TIME PERIODS - HAS OUTCOME CHANGED OVER TIME

The objective of this study was to see whether outcome of infants of l arger birth weight (1,000-1,499 grams) has changed with advances in ne onatology. The outcome of infants born in a recent time period (1989-1 991) was compared with that of infants born previously in 1984-1986 an d 1979-1981. Univariate analyses were conducted on the association of medical risk factors and date of birth with outcome. More than 90% of infants in each time period were neurologically normal and more than 8 0% were cognitively normal. Predictor variables were intracranial hemo rrhage for poor neurologic outcome and days on oxygen for poor cogniti ve outcome. We found that neurodevelopmental outcome was stable over t hree time periods.