DESIGN, SYNTHESIS, AND EVALUATION OF POTENTIAL GAR AND AICAR TRANSFORMYLASE INHIBITORS

Authors
BOGER DL KOCHANNY MJ CAI H WYATT D KITOS PA WARREN MS RAMCHARAN J GOOLJARSINGH LT BENKOVIC SJ
Citation
Dl. Boger et al., DESIGN, SYNTHESIS, AND EVALUATION OF POTENTIAL GAR AND AICAR TRANSFORMYLASE INHIBITORS, Bioorganic & medicinal chemistry, 6(6), 1998, pp. 643-659
Citations number
28
Categorie Soggetti
Biology,"Chemistry Medicinal","Chemistry Inorganic & Nuclear
Journal title
Bioorganic & medicinal chemistry → ACNP
ISSN journal
09680896
Volume
6
Issue
6
Year of publication
1998
Pages
643 - 659
Database
ISI
SICI code
0968-0896(1998)6:6<643:DSAEOP>2.0.ZU;2-N
Abstract
The synthesis and evaluation of 1-4 as potential inhibitors of GAR Tfa se and AICAR Tfase are detailed. (C) 1998 Elsevier Science Ltd. All ri ghts reserved.