Introduction, - Empty sella syndrome is sometimes associated with ante
rior pituitary insufficiency, the latter being mostly partial or disso
ciated. Exegesis. - We report a case of a profound panhypopituitarism
revealing art empty sella syndrome. This case shows that empty sella s
yndrome, although a generally benign and asymptomatic condition, can b
e associated with hypopituitarism. Conclusion. - In case of empty sell
a syndrome, especially if an endocrine dysfunction is clinically suspe
cted, minimal hormonal analysis must be requested. (C) 1998 Elsevier,
Paris.