SYNTHESIS OF METHYL-DERIVATIVES OF LINEAR AND ANGULAR THIENOCOUMARINSAND THIOPYRANOCOUMARINS

Authors
RODIGHIERO P PASTORINI G CHILIN A MAROTTO A
Citation
P. Rodighiero et al., SYNTHESIS OF METHYL-DERIVATIVES OF LINEAR AND ANGULAR THIENOCOUMARINSAND THIOPYRANOCOUMARINS, Journal of heterocyclic chemistry, 35(4), 1998, pp. 847-852
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
35
Issue
4
Year of publication
1998
Pages
847 - 852
Database
ISI
SICI code
0022-152X(1998)35:4<847:SOMOLA>2.0.ZU;2-T
Abstract
New linear and angular thienocoumarins and thiopyranocoumarins were sy nthesized. The key intermediates were appropriate methyl derivatives o f 7-mercaptocoumarin, which were condensed with chloroketones or propa rgyl chloride. Thioethers were cyclized under various conditions in or der to determine which methods produced the best yields of the desired thienocoumarins 15, 16, 17, 18, 22, 23, 24, 27 and thiopyranocoumarin s 28 and 29.