Chronic renal failure is associated with distal symmetrical axonal neu
ropathy. We report a 50-year-old man who suffered from chronic renal f
ailure due to benign enlargement of the prostate. He presented with fe
ver and rapidly developing pure motor neuropathy. The nerve conduction
velocity was slow and the F response delayed, suggestive of demyelina
ting neuropathy. A sural nerve biopsy specimen was also consistent wit
h demyelination and axonal changes. This patient improved significantl
y following intermittent catheterization and a short course of norflox
acin. Renal failure may be associated with reversible motor neuropathy
.