Objective: To determine whether the spatial resolution that can be ach
ieved with currently available MR devices is adequate for the evaluati
on of skin disease. Material and Methods: We correlated high-resolutio
n MR images of the skin with dermatohistopathology in 26 patients. The
examinations were carried out on a 1.0 T imager using a commercially
available surface coil (ID 7.5 cm) and optimized SE and GE sequences.
Image quality was assessed by four readers on a questionnaire. Results
. The visualization of the dermis, subcutaneous tissue, and muscle fas
cia allowed a pattern analysis that gave findings identical to;those a
t dermatohistopathology. It was possible to distinguish septal from lo
bular panniculitis, and lipatrophia from sclerodermia. Images with con
trast media infusion were useful in the differential diagnosis. Conclu
sion. High-resolution MR imaging may narrow down the differential diag
nosis of various skin diseases and may help to reduce the number of sk
in biopsies on certain indications.