ASYMMETRIC-SYNTHESIS BY ENZYMATIC-HYDROLYSIS OF PROCHIRAL DIENOL DIACETATE

Authors
DUHAMEL P RENOUF P CAHARD D YEBGA A POIRIER JM
Citation
P. Duhamel et al., ASYMMETRIC-SYNTHESIS BY ENZYMATIC-HYDROLYSIS OF PROCHIRAL DIENOL DIACETATE, Tetrahedron : asymmetry, 4(12), 1993, pp. 2447-2450
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
4
Issue
12
Year of publication
1993
Pages
2447 - 2450
Database
ISI
SICI code
0957-4166(1993)4:12<2447:ABEOPD>2.0.ZU;2-O
Abstract
Enzymatic hydrolysis of prochiral dienol diacetate 1 by Candida cylind racea lipase (C C L) leads to the keto enol acetate 2 in high yield wi th an enantiomeric excess > 98 %. The S configuration of the asymmetri c center was assigned.