THE ROLE OF ADHESION MOLECULES IN ALLERGIC INFLAMMATION AND THEIR SUITABILITY AS TARGETS OF ANTIALLERGIC THERAPY

Authors
SCHLEIMER RP BOCHNER BS
Citation
Rp. Schleimer et Bs. Bochner, THE ROLE OF ADHESION MOLECULES IN ALLERGIC INFLAMMATION AND THEIR SUITABILITY AS TARGETS OF ANTIALLERGIC THERAPY, Clinical and experimental allergy, 28, 1998, pp. 15-23
Citations number
92
Categorie Soggetti
Allergy,Immunology
Journal title
Clinical and experimental allergy → ACNP
ISSN journal
09547894
Volume
28
Year of publication
1998
Supplement
3
Pages
15 - 23
Database
ISI
SICI code
0954-7894(1998)28:<15:TROAMI>2.0.ZU;2-6
Abstract
Adhesion molecules on leukocytes and tissue-resident cells are now kno wn to mediate steps of the allergic inflammation response. Blockade of adhesion pathways is being actively explored as a potential strategy to therapeutically manage allergic diseases. The various adhesion mole cules and their counterligands are discussed with respect to evidence supporting their role in allergic inflammation and suitability as ther apeutic targets.