DETERMINATION OF THE ENANTIOMERIC EXCESS OF ALPHA-HYDROXY ACIDS

Authors
CAVELIER F GOMEZ S JACQUIER R LLINARES M MERCADIER JL PETRUS C VERDUCCI J
Citation
F. Cavelier et al., DETERMINATION OF THE ENANTIOMERIC EXCESS OF ALPHA-HYDROXY ACIDS, Tetrahedron : asymmetry, 4(12), 1993, pp. 2495-2500
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
4
Issue
12
Year of publication
1993
Pages
2495 - 2500
Database
ISI
SICI code
0957-4166(1993)4:12<2495:DOTEEO>2.0.ZU;2-#
Abstract
This work describes a convenient and accurate method for optical purit y determination of a-hydroxy acids. Their derivatization with commerci ally available valine methyl ester affords diastereoisomers easily sep arable by HPLC using achiral C-18 columns.