SYNTHESIS AND RESOLUTION OF RACEMIC 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL

Authors
SMRCINA M VYSKOCIL S POLIVKOVA J POLAKOVA J KOCOVSKY P
Citation
M. Smrcina et al., SYNTHESIS AND RESOLUTION OF RACEMIC 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL, Collection of Czechoslovak Chemical Communications, 61(10), 1996, pp. 1520-1524
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
61
Issue
10
Year of publication
1996
Pages
1520 - 1524
Database
ISI
SICI code
0010-0765(1996)61:10<1520:SAROR2>2.0.ZU;2-C
Abstract
The title compound 3 has been prepared via a highly selective, Cu(II)- mediated cross-coupling of 2-aminonaphthalene 1 and 2-naphthol 2 and r esolved into enantiomers via crystallization of diastereoisomeric salt s with (1S)-(+)-10-camphorsulfonic acid. The method has been optimized and the use of chromatography eliminated.