FUNCTIONAL GENOMICS IN THE POST-GENOME ERA

As the biomedical research community enters the post-genome era, study ing gene expression patterns and phenotypes in model organisms will be an important part of analyzing the role of genes in human health and disease. New technologies involving DNA chips will improve the ability to evaluate the differential expression of a large number of genes si multaneously. Also, new approaches for generating mutations in mice wi ll significantly decrease the cost and increase the rate of generating mutant lines that model human disease. (C) 1998 Elsevier Science B.V. All rights reserved.