HEMATOMETRA SECONDARY TO ANTICOAGULANT RODENTICIDE TOXICITY

An adult, intact female Australian shepherd presented for frank vagina l bleeding of unknown duration. The only coagulation profile abnormali ty upon presentation was mild prolongation of the partial thromboplast in time (PTT). The uterus was removed at surgery and contained a large amount of coagulated blood. Clotting profiles were markedly abnormal 48 hours postoperatively. Serum analysis was positive for brodifacoum, an anticoagulant rodenticide. Preoperative coagulation was most likel y normalized by vitamin K-1 therapy administered prior to presentation . The only manifestation of anticoagulant rodenticide was hematometra. Rodenticide intoxication should be considered in the differential dia gnosis list of hematometra or metrorrhagia.