Biotechnological approaches have great potential in rapid expansion of
livestock through newer, cheaper and reliable means of producing effe
ctive vaccines and diagnostics for animal health care management. In t
his paper, the results of research work done at the National Biotechno
logy Centre of this Institute, during the past one decade on the appli
cation of molecular biological and hybridoma technologies for developm
ent of improved diagnostics and effective vaccines against some econom
ically important animal diseases such as rinderpest, bluetongue, bovin
e herpes virus-1 infection, poxvirus infection, infectious bursal dise
ase, clostridiosis, salmonellosis and pasteurellosis were reviewed.