CARDIOPULMONARY BYPASS WITH DANAPAROID SODIUM AND ANCROD IN HEPARIN-INDUCED THROMBOCYTOPENIA

Authors
KANAGASABAY RR UNSWORTHWHITE MJ ROBINSON G BEVAN D FARNSWORTH G HAXBY EJ SMITH EEJ
Citation
Rr. Kanagasabay et al., CARDIOPULMONARY BYPASS WITH DANAPAROID SODIUM AND ANCROD IN HEPARIN-INDUCED THROMBOCYTOPENIA, The Annals of thoracic surgery, 66(2), 1998, pp. 567-569
Citations number
11
Categorie Soggetti
Surgery,"Cardiac & Cardiovascular System","Respiratory System
Journal title
The Annals of thoracic surgery → ACNP
ISSN journal
00034975
Volume
66
Issue
2
Year of publication
1998
Pages
567 - 569
Database
ISI
SICI code
0003-4975(1998)66:2<567:CBWDSA>2.0.ZU;2-E
Abstract
Heparin is the standard anticoagulant for patients undergoing cardiopu lmonary bypass. There are some patients for whom heparin is unsuitable and ancrod (a defibrino-genating enzyme) has been used as an alternat ive. We present a patient with heparin-induced thrombocytopenia in who m treatment ancrod was ineffective. The addition of danaparoid sodium (a heparinoid) allowed safe cardiopulmonary bypass. We discuss the rea sons for this and suggest that the combination of ancrod and danaparoi d sodium is a logical one in such cases. (C) 1998 by The Society of Th oracic Surgeons.