Although the precise definition of multiple system atrophy has been di
fficult, a recent consensus in diagnostic criteria for multiple system
atrophy has been achieved. This should lead to progress in defining t
he underlying pathophysiology of the neuroendocrine, autonomic and mot
or deficits characteristic of multiple system atrophy. Hopefully, thes
e developments will lead to effective treatment. (C) 1998 Lippincott-R
aven Publishers.