ALZHEIMERS-DISEASE AND THE NONCHOLINERGIC ACTIVITIES OF CHOLINESTERASES - A POSSIBLE RELATIONSHIP

Citation
As. Balasubramanian, ALZHEIMERS-DISEASE AND THE NONCHOLINERGIC ACTIVITIES OF CHOLINESTERASES - A POSSIBLE RELATIONSHIP, Current Science (Bangalore), 75(3), 1998, pp. 196-200
Citations number
75
Categorie Soggetti
Multidisciplinary Sciences
Journal title
ISSN journal
00113891
Volume
75
Issue
3
Year of publication
1998
Pages
196 - 200
Database
ISI
SICI code
0011-3891(1998)75:3<196:AATNAO>2.0.ZU;2-5
Abstract
Three of the major features of Alzheimer's disease are, a cholinergic deficit, amyloid beta peptide deposition in plaques and abnormalities in zinc status. A unified hypothesis linking these findings to the non -cholinergic activities of cholinesterases demonstrated by work in the author's laboratory is presented in this article.