INTERSTITIAL PREGNANCY TREATED WITH LOCAL AND SYSTEMIC METHOTREXATE

We present a case of an intact interstitial pregnancy at 6 postmenstru al weeks and 4 days, which was successfully treated by combined local and systemic methotrexate administration. The embryonic cardiac activi ty stopped within 1 min after uneventful ultrasound-guided puncture an d methotrexate instillation of the chorionic sac. While the beta-hCG s erum values returned to normal 59 days sifter local, and 52 days after systemic treatment, the echogenic lesion has reduced in size by 50%, but is still sonographically detectable 7 months after the procedure. This report shows that medical treatment of interstitial pregnancy may be an effective alternative to the surgical approach.